CaseStudy1_Questions
CaseStudy1_Questions.RmdQuestions:
Q: What is the primary outcome of the study? A: The primary outcome of the study is the time to death True: Time to death False: Time to recovery False: Likelihood to require ventilation False: Readmission within 30 days
Q: What is the study design? A: The study is a randomized, controlled trial that compares the effects of dexamethasone with standard care in hospitalized patients with Covid-19. True: RCT False: Observational study False: Secondary analysis of data False: Case study
Q: What was the treated sample size? A: The study treated 2014 patients, having enrolled 6245 patients in total. True: 2104 patients False: 5000 patients False: 9335 patients False: 4321 patients
Q: What analysis was used to assess the primary outcome? A: The primary outcome was assessed using a Cox proportional-hazards model, which compared the time to recovery between the dexamethasone group and the standard care group. T: Cox proportional-hazards model F: Logistic regression F: ANOVA F: Linear regression
Q: What subgroup analyses were performed? A:
Q: What were the results of the primary outcome? A: The results showed that dexamethasone reduced the time to recovery compared to standard care. T: Dexamethasone reduced mortality F: Dexamethasone increased mortality F: Dexamethasone icnreased time to recovery F: Dexamethasone reduced time to recovery
Q: For which patients are dexmethasone recommended? A: Dexamethasone is recommended for patients who are receiving respiratory support, including those on mechanical ventilation or oxygen therapy, as it was shown to reduce mortality in these groups. T: Patients on mechanical ventilation or oxygen therapy F: All hospitalized patients F: Patients with severe Covid-19 symptoms only F: Patients with mild Covid-19 symptoms
Q: For which patients is dexamethasone not recommended? A: Dexamethasone is not recommended for patients who do not require respiratory support, as it did not show a benefit in this group and may even be harmful. Or those who have other contraindications for dexamethasone use. T: Patients not requiring respiratory support F: Patients with severe Covid-19 symptoms F: Patients on mechanical ventilation F: All patients with Covid-19
Q: How was randomization performed? A: Randomization was performed using a computer-generated randomization sequence, which assigned patients to either the dexamethasone group or the standard care group. T: Computer-generated randomization sequence F: Block Randomization based on hospital ward F: Randomization by patient preference F: Stratified randomization by age
Q: What exclusions factors were applied? A: Patients with either indication for, or contraindication to dexamethasone were excluded, and those being treated at sites without access to dexamethasone. T: Patients with indication or contraindication to dexamethasone T: Patients being treated at sites without access to dexamethasone F: Patients with mild Covid-19 symptoms F: Patients with severe Covid-19 symptoms only